Shumet A. Hailu, Robin H. Bogner, Solid‐state surface acidity and pH‐stability profiles of amorphous quinapril hydrochloride and silicate formulations, Journal of Pharmaceutical Sciences, 10.1002/jps.22051, 99, 6, (2786-2799), (2010). Chemical stability evaluates a drug’s susceptibility to degradation (acid, base, oxidant), and is investigated in solution as well as in solid-state, typically with chromatographic methods. Both Ti/SS and Ti/Nb/SS welds were subjected to thermal exposure ranging from 300 °C to 950 °C for 1.5 h. Interface Stability in Solid-State Batteries William D. Richards,† Lincoln J. Miara,‡ Yan Wang,† Jae Chul Kim,† and Gerbrand Ceder*,†,¶,§ †Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States ‡Samsung Advanced Institute of Technology - USA, 255 Main Street, Suite 702, Cambridge, Massachusetts … Reducing the modulation period of the SLL thin film improves the stability of the amorphous Ge–Sb–Te phase. Understanding interface stability in solid-state batteries Y X 1,2 , Y Wang 3, S-H B 2,4 2,5, J C K , L J. Ma 3 G C 1,2 * Abstract | Solid-state batteries (SSBs) using a solid electrolyte show potential for providing improved safety as well as higher energy and power density compared with conventional Li … The solid-state lithium battery is considered as an ideal next-generation energy storage device owing to its high safety, high energy density and low cost. In this Chapter, the major physical stability attributes of drug dosage forms are discussed with focus on the effects of solid-state properties of drug substance and manufacturing processes. In general, the pHeq- and reconstituted pH-stability profiles were essentially identical, but the suspension pH-stability profile deviated from the reconstituted pH-stability profile by 2-3 pH units. The solid-state polymerization obeyed second-order kinetics, and the rate constants were estimated and the values of k 2 ranged from 14.5 to 20.8 kg mol −1 min −1. Stainless steel (SS) and titanium alloys can be welded in the solid-state by high speed oblique impact. The solid-state physical changes involving polymorphs, hydrates, amorphous forms, and the effect of … Solid-state batteries (SSBs) using a solid electrolyte show potential for providing improved safety as well as higher energy and power density compared with conventional Li-ion batteries. The solid state is preferred for many proteins due to their marginal stability in solution. These studies showed that the coating sequence has a significant effect on the element distribution in the as-deposited SLL thin films and the structure of the final product upon solid-state reaction. They were not significantly influenced by the structure of the monoacetate. Solid state pharmaceutical chemicals can break down due along a wide range of different kinetic pathways. In order to determine a drug candidate’s stability, extremes of temperature, chemical aggregation, mechanical force, chemical damage, and other stressors must be applied according to known and suspected degradation pathways. However, the poor ionic conductivity of solid electrolyte and low interfacial stability has hindered the application of solid-state lithium battery. Here, the effect of a niobium (Nb) interlayer on weld strength and thermal stability is evaluated.
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