Endogenous and exogenous antioxidants as a tool to ameliorate male infertility induced by reactive oxygen species. N = 6 rat per group. Asterisk (*) within a bar graph indicates significant difference between the means (P < 0.05). Furthermore, CFLs had no effect on serum levels of luteinizing hormone and sperm count and also, increased abnormal sperm shapes. If you do not receive an email within 10 minutes, your email address may not be registered, Oxidants, Antioxidants and Impact of the Oxidative Status in Male Reproduction. Co-administration of curcumin to morphine-treated rats improved the histopathological alterations induced by morphine in testis and increased the sperm count. This helps increase the sperm count. �fbV��$~a��"�R,Z�@��/ >� endstream endobj 42 0 obj <> endobj 43 0 obj <> endobj 44 0 obj <>stream The effect of curcumin-loaded iron particles on sperm parameters in long term scrotal hyperthermia induced mice. Administration of curcumin significantly reversed sperm viability in the curcumin+sodium arsenite group when compared to the sodium arsenite group (P<0.001). hޔV�n�8��@��{&ͤ ���d/�5!���R7ӯ_R�=N�t��uxH��8Y��%〥�KCE)K#4� This work was supported by grants from the National Natural Science Foundation of China (Grant Number 81401258), Guangdong Natural Science Foundation (Grant Number 2014A030313652), Shenzhen Foundation of Science and Technology (Grant Number JCYJ20140414170821307 and JCYJ20150330102401083), Medical Scientific Research Foundation of Guangdong (Grant Number A2015122). When low‐dose curcumin (10 mg/kg) was administered to diabetic rats, we found that curcumin significantly increased sperm motility and density, and decreased abnormal … 41 0 obj <> endobj 47 0 obj <>/Filter/FlateDecode/ID[<73AB0A30A51E44A8904775134F6B434A>]/Index[41 20]/Info 40 0 R/Length 53/Prev 246941/Root 42 0 R/Size 61/Type/XRef/W[1 2 1]>>stream Curcumin as an atoxic antioxidant can reduce production of NO. Cai Zhiming, Reproductive Medicine Centre, the First Affiliated Hospital of ShenZhen University, Shen Zhen No.2 Hospital, ShenZhen, China. Effect of curcumin on dexamethasone-induced testicular toxicity in mice ... averaged. … The aim of this study was to evaluate the effects of curcumin on sperm count, motility and viability, semen total antioxidant capacity and DNA integrity of rat spermatozoa during semen … The protective effect of curcumin on lead acetate-induced testicular toxicity in: (A) sperm Count; (B) sperm motility; and (C) sperm viability. Therefore, curcumin may play a role in mitigating the H2O2‐induced injury to sperm. Automated semen analysis by SQA Vision® versus the manual approach—A prospective double‐blind study. Altered testicular histology, reduced sperm count, low testosterone level, decreased accessory sex organs weight, enhanced lipid peroxidation along with reduced SOD and catalase activities were observed following K(2)Cr(2)O(7) exposure while curcumin supplementation along with K(2)Cr(2)O(7) exposure had shown to prevent the altered parameters. There was a significant increase in the sperm parameters in Curcumin group compared to the D-galactose group (p<0.05). Although the toxicity/biocompatibility of hydroxyapatite nanoparticles (HAPNPs), a prospective nano-biomaterial, is extensively studied, its interaction on the reproductive system following exposure is less exploited. What does this mean? Effect of curcumin on chromium-induced oxidative ... reduced sperm count, low testosterone level, decreased accessory sex organs weight, enhanced lipid peroxidation along with reduced SOD and catalase activities ... ity, sperm abnormalities leading to infertility (Bonde, 1993). Since modulation of intracellular pH (pHi) and plasma membrane polarization is involved in sperm motility, the present study was conducted to investigate the effect of curcumin on these sperm … min along with aflatoxin ameliorated aflatoxin-induced sperm count, immobilization, and viability, and improved the morphologic characteristics of the sperm. 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